Our CoQ10 Quality Commitment
Natural vs. Synthetic
Natural CoQ10 is produced by microbial (yeast or bacteria) fermentation, resulting in the production of the desirable trans isomer, the form identical in structure to CoQ10 made by the human body. This allows for optimal bioactivity. There is no residual yeast or bacteria in the final product.
Synthetic CoQ10 is produced as the result of a part fermentation, part synthetic process where the compound solanesol is extracted from tobacco leaf. The synthetic processing of this compound produces both cis and trans isomers. The cis isomer is an undesirable molecule as it does not occur naturally and is considered an impurity.
All of our CoQ10 powders, liquids, and softgels contain 100% natural, fermented Japanese material and are third party tested.
Natural CoQ10 is produced by microbial (yeast or bacteria) fermentation, resulting in the production of the desirable trans isomer, the form identical in structure to CoQ10 made by the human body. This allows for optimal bioactivity. There is no residual yeast or bacteria in the final product.
Synthetic CoQ10 is produced as the result of a part fermentation, part synthetic process where the compound solanesol is extracted from tobacco leaf. The synthetic processing of this compound produces both cis and trans isomers. The cis isomer is an undesirable molecule as it does not occur naturally and is considered an impurity.
All of our CoQ10 powders, liquids, and softgels contain 100% natural, fermented Japanese material and are third party tested.
| CONSISTENCY During recent periods of short supply and high demand, we continued to offer only 100% natural, fermented Japanese CoQ10, without substituting, switching or blending with readily available and attractively priced synthetic versions. |
Absorption and Pharmacokinetics:
Powder, Oil-based and HydrosolubleTM CoQ10
CoQ10 absorption takes place as follows:
- As a fat soluble nutrient, it is emulsified with fats in the
intestines and formed into micelles for absorption into the gut - After it is absorbed, it enters the lymphatic system and
travels to the blood stream - Plasma levels peak within 5-10 hours and half-life is
approximately 34 hours - Maximal serum concentrations are reached after about
3 weeks of continuous use
A critical factor in CoQ10 absorption is the surface area
available for interaction with bile salts, the body’s natural
emulsifiers. CoQ10 in powder-filled capsules taken with
lipid-containing meals allows for it to be solubilized by fats,
enhancing surface area for emulsification and absorption.
CoQ10 dissolved in oil, such as our EPA/DHA-CoQ10 softgels
and liquid, is absorbed similarly but has the advantage of
being pre-solubilized in fat. This means it does not require
proximity to meals of lipid composition.

Surface area is also increased with Hydrosoluble. CoQ10, or Q-GelR. In this case, the particle size has been reduced in the patented Bio-SolvR process to a sub-micron size, greatly enhancing the surface area of the CoQ10 which can be acted upon by the natural emulsifers (bile salts) in the intestinal tract.
The advantage is enhanced micellization and absorption. Absorption in this case is also independent of composition of meals.
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